Columbus

The name Andelyn Biosciences honors Andrew and Evelyn, two pioneering gene therapy patients. Andrew received the first U.S. DMD gene therapy; Evelyn helped create SMA’s first approved treatment. Andelyn Biosciences manufactures gene therapies that turn hope into reality for families facing rare diseases. But they faced a critical challenge: after two years struggling with a failing NAC solution that was too complex to deploy and impossible to manage effectively, they had zero cybersecurity policies protecting their manufacturing environment. Every vulnerable day risked not their business, but the future treatments that could save children like Andrew and Evelyn. Join Bryan Holmes, VP of Information Technology, as he shares their dramatic transformation using Elisity’s identity-based microsegmentation platform. Discover how he achieved what seemed impossible: easy deployment, simple management, and dramatically higher security. In just 90 days, his small IT team deployed 2,700 active security policies without agents, without downtime, and without the operational complexity that had defeated them before. Learn how he moved from a failed NAC implementation that required specialized expertise he didn’t have, to a modern microsegmentation solution so intuitive that his 3-person IT team could deploy and manage enterprise-grade protection. This isn’t just about deploying technology—it’s about finding solutions that actually work for real teams with real constraints, while honoring the courage of two brave children and ensuring every gene therapy batch we manufacture safely reaches the patients counting on them. Discover the practical strategies, hard-won lessons, and bold decisions that enabled a 300-person company to achieve higher security with lower complexity, proving that the right approach makes all the difference in protecting life-critical manufacturing operations.

Things keep changing. And changing.  Security professionals need to secure all the things, and all the new things. We’ll discuss tactics and share resources for getting on top of the information overload and keeping up – without losing your mind.

Data security has been around for decades, and yet, it still feels like an unsolvable puzzle. Legacy technologies are typically resource-intensive, find just a small portion of companies’ sensitive data, and produce a ton of false positives. The impact to operations is often so significant that businesses never move their DLP out of monitoring mode. Attend our session to learn:
• Why traditional approaches to data security have failed
• How AI and context are revolutionizing data security
• Where to maximize the value of your existing security investments
• What you can do to secure your Gen AI rollouts With the right strategy and technology, you can transform your data from a liability to a well-managed asset.

Join Jake Mickley, Senior Solutions Architect, for an engaging session on “Offense-Driven Defense.” Jake will challenge conventional risk assessment practices and unveil how focusing on real-world exploitability and impact can revolutionize your security approach. Drawing from insights gathered across more than 150,000 autonomous pentests, he’ll share compelling stories and actionable lessons that show how viewing your cyber terrain through an attacker’s lens can uncover hidden vulnerabilities, optimize resource allocation, and strengthen your defenses against advanced threats. Don’t miss this opportunity to learn from a leading industry practitioner on why it’s time to “go hack yourself” and build resilience in today’s borderless threat environment.

As cyber threats continue to evolve, traditional passwords have become one of the weakest links in enterprise security – easily guessed, reused, or phished. This presentation explores modern password less authentication solutions that enhance both security and user experience. Focusing on technologies such as Windows Hello for Business, FIDO2 security keys, and web sign-in for password less multi-factor authentication (MFA), We share deployment insights on how organizations can eliminate passwords altogether while maintaining strong, user-friendly access controls. Attendees will gain insight into how these technologies work, and why they are critical in defending against password stuffing, phishing attacks, and other credential-based threats. Join us to learn how going password less is not only possible, but necessary for a more secure and modern digital environment.

Ransomware attacks continue to be extremely lucrative, with ransom demands and recovery costs bleeding victim organizations for millions of dollars. And things change fast in this space – RaaS groups rise and fall with law enforcement takedowns, or disband and reorganize under different brands, so it can all be a little confusing. Each quarter, the Halcyon team of ransomware experts put together a RaaS power rankings guide for the ransomware threat landscape.

Data resilience is becoming a cornerstone of modern industry, ensuring continuous access to critical information that drives smarter decision-making, automation, and innovation. As digital infrastructures grow more complex and interconnected, the need for robust cybersecurity becomes paramount. AI now throws a whole new point of concern—making it even more critical to ensure your data is secure, as intelligent systems rely heavily on accurate, trusted information. Threats such as ransomware, data corruption, system failures, and malicious attacks underscore the importance of protecting data at every stage—from creation and transmission to storage and recovery. Data resiliency plays a vital role in cybersecurity—because if your data isn’t recoverable, how long would it take your organization to recover, if at all? Ensuring that your infrastructure can restore vital data is essential for maintaining business continuity. Investing in data security and resilient infrastructure is not just a technical requirement—it’s a strategic necessity for sustainable and secure operations.

Key Topics:

• Ransomware, phishing, and advanced persistent threats (APTs).
• Optimizing operations and improving security through Orchestration and Automation.
• Understanding the impact of AI and IoT on security vulnerabilities.

Why It Matters:
Staying informed about the latest threats helps leaders anticipate and prepare for risks that can disrupt operations.

The cybersecurity landscape has experienced a fundamental paradigm shift that most organizations haven’t recognized yet: while security teams continue deploying signature-based detection and traditional machine learning models, cybercriminals have weaponized Large Language Models to launch fully automated, AI-powered attack pipelines that consistently evade legacy security systems. In this eye-opening keynote, cybersecurity veteran Joshua Bass reveals how attackers are jailbreaking open-source models like Mistral and LLaMA to generate polymorphic malware and hyper-personalized social engineering attacks, then introduces a revolutionary approach to threat detection that moves from pattern matching to intent reasoning, demonstrating how AI-native defenses can effectively counter attack vectors that completely bypass traditional tools. Attendees will leave with actionable insights about the current threat landscape, practical techniques for identifying AI-generated attacks, and a clear understanding of why the future of cybersecurity lies not in detecting what attacks look like, but in reasoning about what they’re trying to accomplish.